Equally effective for all Stage I tumors, regardless of age and site, are external beam radiation therapy and intracavitary or interstitial radiation therapy. Smaller lesions are sometimes treated with only intracavitary or interstitial radiation therapy.
Five-Year Survival 70 to 80 percent
Investigational
• Meticulous surgical staging before radiation therapy.
• Chemotherapy given simultaneously with radiation therapy. Chemotherapeutic regimens under investigation
include mitomycin-C + 5-fluorouracil (5-FU) with or without cisplatin .
• Radiation therapy with heat (hyperthermia).
Stage II (squamous cell carcinoma and adenocarcinoma)
TNM T2, N0, M0
The carcinoma involves the adjacent vaginal tissue but has not extended to the pelvic wall.
Standard Treatment External beam radiation and interstitial or intracavitary radiation.
